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  • Biogen advances Alzheimer’s tau program despite midphase miss

Biogen advances Alzheimer’s tau program despite midphase miss

  • May 14, 2026

A phase 2 trial of Biogen and Ionis Pharmaceuticals’ tau-targeting candidate missed its primary endpoint. But while the Alzheimer’s disease trial failed to yield the hoped-for dose-response data, reductions in tau pathology and cognitive benefits persuaded Biogen to commit to registrational development.

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