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  • BioNTech advances DualityBio ADC into phase 3 with half the patients of Merck-Daiichi rival

BioNTech advances DualityBio ADC into phase 3 with half the patients of Merck-Daiichi rival

  • February 27, 2026

BioNTech and partner DualityBio are accelerating the development of their B7-H3 ADC into a phase 3 trial for metastatic castration-resistant prostate cancer (mCRPC). With encouraging phase 1/2 data, the partners are aiming to achieve success with a trial roughly half the size of the competing program from Merck & Co. and Daiichi Sankyo.

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