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  • Roche reports another phase 3 multiple sclerosis win, but deaths add to safety questions

Roche reports another phase 3 multiple sclerosis win, but deaths add to safety questions

  • March 2, 2026

A second phase 3 study of Roche’s fenebrutinib in relapsing multiple sclerosis has hit its primary endpoint, positioning the company to submit the BTK inhibitor for approval. But the discovery that more patients died on fenebrutinib than on the control drug has spurred further analyses by Roche.

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