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  • FDA official confirms plausible mechanism principles not exclusive to bespoke gene therapies

FDA official confirms plausible mechanism principles not exclusive to bespoke gene therapies

  • April 14, 2026

The FDA’s newly launched plausible mechanism framework may have been forged in the image of individualized therapies, but its principles are not confined to the bespoke, Teresa Buracchio, M.D., head of the FDA’s Office of Neuroscience, told Fierce.

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